Computational Medicine: Tools and Challenges by Zlatko Trajanoski

By Zlatko Trajanoski

Computational methodologies and modeling play a turning out to be position for investigating mechanisms, and for the prognosis and treatment of human illnesses. This growth gave upward push to computational medication, an interdisciplinary box on the interface of desktop technology and drugs. the focus of computational medication lies within the improvement of information research equipment and mathematical modeling in addition to computational simulation suggestions in particular addressing scientific difficulties. during this ebook, we current a few computational medication subject matters at numerous scales: from molecules to cells, organs, and organisms. on the molecular point, instruments for the research of genome adaptations in addition to cloud computing assets for scientific genetics are reviewed. Then, an research of gene expression information and the applying to the characterization of microbial groups are highlighted. on the protein point, varieties of analyses for mass spectrometry info are reviewed: categorised quantitative proteomics and lipidomics, by way of protein series research and a 3D constitution and drug layout bankruptcy. eventually, 3 chapters on scientific functions specialize in the combination of biomolecular and medical info for melanoma learn, biomarker discovery, and network-based tools for computational diagnostics.

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